D-Serine
General info
The NMDA (N-methyl-D-aspartate) receptor (also known as NMDAR), is a glutamate receptor and ion channel protein found in nerve cells. It is activated when glutamate and glycine (or D-serine) bind to it, and when activated it allows positively charged ions to flow through the cell membrane.[1]
D-Serine supplementation can reduce symptoms of cognitive decline. It is also able to reduce symptoms of diseases characterized by reduced NMDA signaling, which includes cocaine dependence and schizophrenia.[2]
D-Serine is an obligatory endogenous coagonist of the N-methyl-D-aspartate receptor, functioning in vivo as a specific and potent full agonist at the NMDAR-associated glycine (GLY) modulatory site (GMS).[3]
Other interesting links OCD, Glycine - https://www.hindawi.com/archive/2014/859735/
References
- ↑ NMDA Receptor, Wikipedia, https://en.wikipedia.org/wiki/NMDA_receptor
- ↑ D-Serine', Examine, https://examine.com/supplements/d-serine/
- ↑ D-Serine in Neuropsychiatric Disorders: New Advances,Hindawi,https://www.hindawi.com/archive/2014/859735/
NMDA Wikipedia page:
