Oxidative Stress - Revision history

Roel Van de Paar at 01:28, 13 July 2017

2017-07-13T01:28:13Z

Roel Van de Paar at 04:19, 27 June 2017

2017-06-27T04:19:30Z

Roel Van de Paar: Created page with "== Oxidative Stress == '''Oxidative stress theory for adult onset of psychosis:''' Oxidative stresses gradually increase until GSH (Glutathione) and MT (Metallothionein) pro..."

2017-06-27T04:19:20Z

Created page with "== Oxidative Stress == '''Oxidative stress theory for adult onset of psychosis:''' Oxidative stresses gradually increase until GSH (Glutathione) and MT (Metallothionein) pro..."

New page

== Oxidative Stress ==

'''Oxidative stress theory for adult onset of psychosis:'''

Oxidative stresses gradually increase until GSH (Glutathione) and MT (Metallothionein) proteins are overwhelmed, resulting in sudden brain inflammation, alteration of NT (neurotransmitter) levels, and disruption of the blood brain barrier. As in Wilson’s Disease, sudden onset of a mental illness in young adulthood may result.<ref name=walsh_imbalances>Biochemical imbalances in mental health populations, William J. Walsh PhD, Walsh Institute, http://www.walshinstitute.org/uploads/1/7/9/9/17997321/biochemical_imbalances_in_mental_health_populations.pdf</ref>

''Define: psychosis:'' a severe mental disorder in which thought and emotions are so impaired that contact is lost with external reality.<ref>define: psychosis, Google, https://www.google.com/search?q=define%3Apsychosis</ref>

All major phenotypes of schizophrenia involve severe oxidative stress, [and] oxidative overload depletes GSH and reduces glutamate activity at NMDA receptors.<ref name="walsh_imbalances" />

Abnormal methylation and severe oxidative stress are major causes of epigenetic errors, [and] greater than 95% of schizophrenics exhibit abnormal methylation or oxidative overload.<ref name="walsh_imbalances" />

''Define: schizophrenia:'' a long-term mental disorder of a type involving a breakdown in the relation between thought, emotion, and behaviour, leading to faulty perception, unfitting actions and feelings, withdrawal from reality and personal relationships into fantasy and delusion, and a sense of mental fragmentation.<ref>define: schizophrenia, Google, https://www.google.com/search?q=define%3Aschizophrenia (edited)</ref>

== References ==
<references />

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 ''Define: schizophrenia:'' a long-term mental disorder of a type involving a breakdown in the relation between thought, emotion, and behaviour, leading to faulty perception, unfitting actions and feelings, withdrawal from reality and personal relationships into fantasy and delusion, and a sense of mental fragmentation.<ref>define: schizophrenia, Google, https://www.google.com/search?q=define%3Aschizophrenia (edited)</ref>
 == References ==
 <references />