Calcium - Revision history

Roel Van de Paar at 00:50, 8 April 2017

2017-04-08T00:50:02Z

Roel Van de Paar at 00:46, 8 April 2017

2017-04-08T00:46:03Z

Roel Van de Paar at 00:44, 8 April 2017

2017-04-08T00:44:54Z

Roel Van de Paar at 00:42, 8 April 2017

2017-04-08T00:42:49Z

Roel Van de Paar: /* Calcium, Vitamin D & Vitamin K2 */

2017-04-08T00:26:59Z

‎Calcium, Vitamin D & Vitamin K2

Roel Van de Paar at 23:40, 7 April 2017

2017-04-07T23:40:33Z

Roel Van de Paar: Roel Van de Paar moved page Vitamin D to Calcium

2017-04-07T23:35:25Z

Roel Van de Paar moved page Vitamin D to Calcium

Roel Van de Paar at 23:35, 7 April 2017

2017-04-07T23:35:05Z

Roel Van de Paar at 23:33, 7 April 2017

2017-04-07T23:33:53Z

Roel Van de Paar at 23:21, 7 April 2017

2017-04-07T23:21:20Z

@@ Line 17: / Line 17: @@
 Note; There are two main types of blood thinners: 1) Anticoagulants, such as heparin or warfarin (also called Coumadin), work on chemical reactions in your body to lengthen the time it takes to form a blood clot. 2) Antiplatelet drugs, such as aspirin, prevent blood cells called platelets from clumping together to form a clot.<ref>Blood Thinners - Also called: Anti-platelet drugs, Anticoagulants,https://medlineplus.gov/bloodthinners.html</ref>
 == '''Hypothesis''' ==
@@ Line 22: / Line 26: @@
 * Calcium should be combined with Vitamin D and Vitamin K2 (especially MK-7) to prevent CHD
 * Care should be taken when dosing Vitamin K2 MK-7 when combined with an anticoagulant
-** It is not clear if Vitamin K2 MK-7 will affect an Antiplatelet like baby aspirin (to be researched)
+** It seems possible to administer Vitamin K2 MK-7 together with baby aspirin according to Dr. Stephen Sinatra
 == References ==
 <references />

@@ Line 22: / Line 22: @@
 * Calcium should be combined with Vitamin D and Vitamin K2 (especially MK-7) to prevent CHD
 * Care should be taken when dosing Vitamin K2 MK-7 when combined with an anticoagulant
 == References ==
 <references />

← Older revision		Revision as of 00:44, 8 April 2017
Line 15:		Line 15:

	MK-7 induced more complete carboxylation of osteocalcin, and hematologists should be aware that preparations supplying 50 ug/d or more of MK-7 may interfere with oral anticoagulant treatment in a clinically relevant way.<ref>Vitamin K–containing dietary supplements: comparison of synthetic vitamin K1 and natto-derived menaquinone-7, www.bloodjournal.org/content/bloodjournal/109/8/3279.full.pdf</ref>		MK-7 induced more complete carboxylation of osteocalcin, and hematologists should be aware that preparations supplying 50 ug/d or more of MK-7 may interfere with oral anticoagulant treatment in a clinically relevant way.<ref>Vitamin K–containing dietary supplements: comparison of synthetic vitamin K1 and natto-derived menaquinone-7, www.bloodjournal.org/content/bloodjournal/109/8/3279.full.pdf</ref>
		+
		+	Note; There are two main types of blood thinners: 1) Anticoagulants, such as heparin or warfarin (also called Coumadin), work on chemical reactions in your body to lengthen the time it takes to form a blood clot. 2) Antiplatelet drugs, such as aspirin, prevent blood cells called platelets from clumping together to form a clot.<ref>Blood Thinners - Also called: Anti-platelet drugs, Anticoagulants,https://medlineplus.gov/bloodthinners.html</ref>

	== '''Hypothesis''' ==		== '''Hypothesis''' ==

@@ Line 13: / Line 13: @@
 Long-chain menaquinones (MK-7 and higher) turned out to have the most beneficial effects on cardiovascular disease, with a mortality risk reduction of 9% for each 10 µg/day of extra intake.<ref name="k2rotterdam" />
 == '''Hypothesis''' ==
 * Calcium should be combined with Vitamin D and Vitamin K2 (especially MK-7) to prevent CHD
+* Care should be taken when dosing Vitamin K2 MK-7 when combined with an anticoagulant
 == References ==
 <references />

@@ Line 1: / Line 1: @@
 == Calcium, Vitamin D & Vitamin K2 ==
-Vitamin K1: Phytonadione
+Vitamin K1: Phytonadione<br>
 Vitamin K2: Menaquinone (various forms, MK-n)

← Older revision	Revision as of 23:35, 7 April 2017
(No difference)

@@ Line 10: / Line 10: @@
 http://jamanetwork.com/journals/jamainternalmedicine/fullarticle/413032</ref>
-After extensive databases had been constructed for the vitamin K1- and vitamin K2-content of various food items, population-based studies were initiated to correlate vitamin K intake with cardiovascular disease. In a first survey, Geleijnse et al. demonstrated that vitamin K2 intake is inversely correlated with cardiovascular disease and mortality. Remarkably, no association was found with the intake of vitamin K1.<ref>Vitamin K: the effect on health beyond coagulation – an overview, Cees Vermeer, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321262</ref><ref>The Rotterdam Study Dietary Intake of Menaquinone (Vitamin K2) Is Associated with a Reduced Risk of Coronary Heart Disease: The Rotterdam Study, http://jn.nutrition.org/content/134/11/3100.full.pdf</ref>
+After extensive databases had been constructed for the vitamin K1- and vitamin K2-content of various food items, population-based studies were initiated to correlate vitamin K intake with cardiovascular disease. In a first survey, Geleijnse et al. demonstrated that vitamin K2 intake is inversely correlated with cardiovascular disease and mortality. Remarkably, no association was found with the intake of vitamin K1.<ref>Vitamin K: the effect on health beyond coagulation – an overview, Cees Vermeer, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321262</ref><ref name=k2rotterdam>Dietary Intake of Menaquinone (Vitamin K2) Is Associated with a Reduced Risk of Coronary Heart Disease: The Rotterdam Study, http://jn.nutrition.org/content/134/11/3100.full.pdf</ref>
-Long-chain menaquinones (MK-7 and higher) turned out to have the most beneficial effects on cardiovascular disease, with a mortality risk reduction of 9% for each 10 µg/day of extra intake.<ref>The Rotterdam Study Dietary Intake of Menaquinone (Vitamin K2) Is Associated with a Reduced Risk of Coronary Heart Disease: The Rotterdam Study, http://jn.nutrition.org/content/134/11/3100.full.pdf</ref>
+Long-chain menaquinones (MK-7 and higher) turned out to have the most beneficial effects on cardiovascular disease, with a mortality risk reduction of 9% for each 10 µg/day of extra intake.<ref name="k2rotterdam" />
 == Hypothesis ==

@@ Line 3: / Line 3: @@
 Randomised studies suggest that calcium supplements <u>without</u> coadministered vitamin D are associated with an increased incidence of myocardial infarction. <ref>Effect of calcium supplements on risk of myocardial
 infarction and cardiovascular events: meta-analysis, BMJ 2010;341:c3691 doi:10.1136/bmj.c3691, http://www.bmj.com/content/bmj/341/bmj.c3691.full.pdf</ref>
 == References ==
 <references />